입증과 신뢰

미국 AAFCO CHAPTER 4 Regulation Expression of Nutritional information

Recommended concentrations for maintenance of body weight at an average caloric intake for dogs of a given optimum

위 규정 참조 최적 칼로리 섭취량에서 체중 유지를 위해 권장되는 농도 설계 되었습니다.

유럽 3.3. FEDIAF SUBSTANTIATION OF NUTRIENT RECOMMENDATION TABLES FOR COMPLETE DOG FOOD

Total protein (Reproduction) The recommendation for protein assumes the diet contains some carbohydrate to decrease the risk of hypoglycaemia in the bitch and neonatal mortality. If carbohydrate is absent or at a very low level, the protein requirement is much higher, and may be double (Kienzle E et al. 1985, Kienzle E et al. 1989, Romsos DR et al. 1981). Total protein (Growth) For practical foods made from cereals and various animal by-products, the crude protein level needed for maximum nitrogen retention appears to be about 25 per cent dry matter for newly weaned puppies, whereas for puppies over 14 weeks of age it is 20 % dry matter (NRC 2006d).

위 규정 참조 총 단백질 권장량은 펫푸드에 탄수화물이 일부 포함되어 있다는 가정하에 설계, 성장기 조단백질 함량은 갓 젖을 뗀 강아지의 경우 약 25%, 생후 14주가 넘은 강아지의 경우 건물 20%로 이에 맞추어 설계하였습니다.

유럽 FEDIAF 3.3.1. Substantiation of nutrient recommendations for complete dog food GENERAL protein

Arginine (All life stages) The arginine requirement increases with increased protein content owing to its role as an intermediate in the urea cycle. For every gram of crude protein above the stated values, an additional 0.01 g of arginine is required (NRC 2006g). See ANNEX 7.4.

위 규정 참조 아르기닌(모든 생애 단계) 은 요소 회로의 중간체 역할로, 단백질 함량 증가 따라 필요량이 증가하므로 적정량 설계하였습니다.

Lysine (nutritional maximum for puppies) It was concluded that the highest no-effect-level of lysine for puppies was 2.91 % DM (energy density 4156 kcal/kg or 17.39 MJ/kg). This is equivalent to 7.0 g/1000 kcal (1.67 g/ MJ) or 2.8 % DM (at 4 kcal/g DM) and this is therefore the FEDIAF maximum for puppy growth.

위 규정 참조 과량의 라이신(기초 사료 0.91% + 보충제 4%)이 강아지의 체중 증가를 감소시킬 수 있어 적정량 2.91% DM을 최대치로 설계했습니다.

유럽 FEDIAF 3.3. FEDIAF SUBSTANTIATION OF NUTRIENT RECOMMENDATION TABLES FOR COMPLETE DOG FOOD

Methionine-Cystine The recommended values are based on a dog food containing a very low taurine content, i.e. <100 mg/kg dry matter (Sanderson SL et al. 2001). For products containing higher levels of taurine the RA for sulphur amino acids can be lower than the values quoted in the table. For further information see taurine section ANNEX 7.3.

위 규정 참조 메티오닌-시스틴(성견) 권장량을 타우린 함량을 고려하여 설계했습니다.

Tyrosine (All life stages) For maximisation of black hair colour, the tyrosine content may need to be 1.5 to 2 times higher than the amount stated (Biourge V et al. 2002, NRC 2006g).

위 규정을 참조로 티로신 함량을 설계 했습니다.

미국 AAFCO CHAPTER 4 Regulation Expression of Nutritional information

It is recommended that the ratio of IU of vitamin E to grams of polyunsaturated fatty acids (PUFA) be > 0.6:1 a diet containin g 50 IU of vitamin E will have a ration > 0.6 :1 when the PUFA contain an additional 0.6 IU of vitamin E for every gram of PUFA Because processing may destroy up to 90% of thiamine in the diet allowances in formulation should be made to ensure t he minimum nutrient concentration thiamine is met after processing .

위 규정 참조 비타민 E와 다중불포화지방산 비율이 0.6:1 이상이 되도록 설계했습니다. 또한 가공 과정에서 파괴율이 높은 비타민 B1(티아민)의 최소 농도를 충족하도록 설계했습니다.

유럽 FEDIAF 3.3.1. Substantiation of nutrient recommendations for complete dog food GENERAL VITAMINS

Vitamin A The FEDIAF maximum is based on the studies reported by Hathcock JN et al. (1990), Goldy GG et al. (1996) a nd Cline JL et al. (1997) in adult dogs. The value is 80 % of the dose that Goldy GG et al. (1996) identified “as may be ap proaching a level that challenges the dog’s ability to maintain normal vitamin A homeostasis” and about 45 % of the n o-adverse-effect intake established by Cline JL et al. (1997) over one year (no detrimental effects on bone health) Furt hermore Hathcock JN et al. (1990) reported an intake at least three times the FEDIAF nutritional maximum as safe in a dult dogs fed for ten months (body growth and haematological indices unaffected). In view of these data the FEDIAF maximum is considered appropriate for all life stages.

위 규정을 참조하여 비타민 A를 영양적 효율과 안전성을 모두 고려하여 정밀 설계했습니다.

유럽 FEDIAF 3.3.1. Substantiation of nutrient recommendations for complete dog food GENERAL VITAMINS

Vitamin D Studies in Great Dane puppies showed that a dietary vitamin D level of 435 IU/100 g DM can affect Ca absorption and may stimulate endochondral ossification disturbances (Tryfonidou MA et al. 2002a, Tryfonidou MA et al. 2002b). Therefore, 320 IU per 100 g DM should be the nutritional maximum for growing giant breed dogs (NRC 2006l). Based on differences in choleca lciferol metabolism between giant breed and small breed puppies (Tryfonidou MA et al. 2002b), 425 IU/100 g DM can be consid ered a safe nutritional maximum for small breed puppies. Since there is no information on maximum safe intakes for adult dog s and breeding bitches, FEDIAF recommends the same nutritional maximum for other life stages as those indicated for puppes. Vitamin E Vitamin E requirements depend on the intake of polyunsaturated fatty acids (PUFA) and the presence of other antioxidants. An increased level of vitamin E may be required if the intake of PUFA is high, particularly from fish oil (Hall J A 1996, Hall JA et al. 2003, Hendriks WH et al. 2002). B Vitamins The recommended minimum of B Vitamins corresponds to NRC (2006i). Adequate Intake (AI) based on bioavailable forms coming from a vitamin premix at the point of consump tion. When no AI level has been identified (and for Vitamin B1), the recommended minimum was based on the NRC Rec ommended Allowance.

위 규정 참조 1. 지나친 비타민D 섭취는 대형견의 칼슘 흡수 및 관절 건강에 무리가 될 수 있어 적정치를 설계했습니다. 2. 비타민E는 다중불포화 지방산과 항산화 영양을 고려했으며 3. 비타민 B는 생체 이용률을 고려하여 설계했습니다.

미국 AFFCO CHAPTER 5 Required Warning and Caution Statements on Medicated Feed Labels

Deficiencies may result from inadequate vitamin K in the diet, disruption of microbial synthesis within the gut (e.g., antibioti c use), inadequate absorption from the intestine, ingestion of vitamin K antagonists (substances that counteract the effect o f vitamin K), or the inability of the liver to utilize available vitamin K. In many species, under normal health conditions endog enous synthesis of vitamin K is sufficient to meet metabolic needs without the requirement for a dietary source. However, in addition to medical conditions and/or use of therapeutic agents that may result in impaired synthesis, absorption or utiliza tion of vitamin K, acquired vitamin K deficiencies may also occur due to other dietary factors. For example, cats fed comme rcial canned diets high in salmon or tuna were found to suffer prolonged coagulation times, gastrointestinal and hepatic he morrhages and death (Strieker et al., 1996). However, these signs were not observed when the animals were given supplem ental phylloquinone (vitamin K1). High dietary intake of sources of long-chain omega-3 fatty acids may also result in signs of vitamin K deficiency (Mameesh and Johnson, 1959; Saker et al., 1998). Because other fat-soluble vitamins may compete an d hence interfere with vitamin K absorption, the addition of high levels of tocopherols to retard oxidation (for either preserva tive or nutritional reasons) in the food may be an aggravating factor in the development of a vitamin K deficiency. Vitamin K is generally known to exist in three forms, two of them are naturally occurring and one is a synthetic analogue which can be found naturally on normal Vitamin K metabolic pathways:It is also noted that menadione, the synthetic vitamin K usually u sed in animal feed, can be added up to levels as high as 1,000 times the dietary requirement without seeing any adverse eff ects in animals, except when used parentally in horses. Vitamin K and the vitamin K active substances serve important roles in providing an essential nutrient in animal diets. The expert panel recommended that Menadione Sodium Bisulfite Compl ex may be used as a safe and suitable source of Vitamin K activity in the food for all animals in the United States in accordan ce with good manufacturing and feeding practices.

위 규정 참조 오메가3 함량과 비타민 K (메나디온 중아황산나트륨)의 상관관계를 유의하여 안전하게 설계하였습니다.